Both coexist on my Mac, and sometimes installations complain about binaries resp. libraries in an incompatible format.
MacPort/DarwinPort lives in /opt/local, Fink lives in /sw.
In order for fine installations I sometimes have to temporarily rename /opt/local resp. /sw.
After the successful installations I rename them back.
I learned this lesson during the installation of ImageMagick on my Mac.
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